Recent Submissions

  • Meet the editors

    The editors are Tyler Pritchard, Editor in Chief, Wyatt Hinkle, Graphic Design Editor, Taylor Self, Technical Sciences Article Editor, James Talbot, Social Sciences Article Editor, McKenna Larson, Content Editor, and Austin Monaghan, Language Editor.
  • Evaluation of the Paris Agreement from a realist and liberalist perspective

    Roth, Kevin
    One of the greatest questions in international relations is how states can work together towards common goals despite having competing interests. This issue is central to the international effort to mitigate climate change. To this date, 185 parties have ratified the Paris Agreement to limit the rise in global temperatures to 1.5 to 2 degrees Celsius. Although this agreement has so far received widespread international support, implementation has proven difficult.
  • Evaluating eribulin's ability to produce a cytokine immune response in lung cancer

    Hinkle, Wyatt A.; Hinz, Trista K.; Gurulé, Natalia J.; Heasley, Lynn E.
    This study aims to examine the ability of Eribulin, a non-taxane microtubule inhibitor, to induce a cytokine immune response similar to that of targeted TKI's in lung cancer cell lines, and furthermore to characterize the cytokine response to general growth arrest therapies compared to specific targeted protein kinase inhibitors such as TKI's.
  • Laboratory spotlight CFCC

    The Colorado Fuel Cell Center (CFCC) is a laboratory on the Colorado School of Mines campus that specializes in the analysis and development of fuel cell systems.
  • Exploring fractional derivatives and trig functions

    Reeder, Leah; Ahrendt, Kevin
    The objective of this research is to become familiar with fractional discrete calculus to the extent that fractional derivatives of discrete trigonometric functions can be taken and understood.
  • Faculty spotlight Dr. Jeffrey King

    Dr. Jeffrey King, of the Materials and Metallurgical Engineering (MME) department, is currently working on research with undergraduates and graduate students in the Nuclear Program at Mines.
  • Preliminary modeling evaluation of water ice extraction from lunar permanently shadowed craters by direct heating of icy regolith

    Machnik, Daniela; Zerpa, Luis
    This work sets the foundation for preliminary modeling of water ice extraction from lunar permanently shadowed craters. Analysis of the research results indicates that (1) favorable phase changes at low temperatures and pressures (though not in-situ conditions) occur and lead to the upward migration of water vapor through the regolith and out of the crater surface, (2) the appearance of the liquid phase significantly reduces the timesteps in the simulation and limits predictive modeling capabilities, (3) adjusting the reservoir model to true lunar conditions requires specific modification of the Fortran base code of TOUGH+, (4) the lack of a void-like phase prevents realistic modeling of mass and energy balance in lunar permanently shadowed craters, (5) a stepwise heat source may yield greater water production for deeper ice reservoirs than a single heat element. The reservoir simulation investigated phase saturation changes of water iced buried in lunar regolith over a three-day period from a 25 W continuous heat source.
  • Three years in the CFCC: the story of Marcos Hernandez

    Hernandez, Marcos
    While the promise of flow batteries continues to grow, they, as with all types of batteries, exhibit issues with performance degradation. I am working to understand and solve these degradation problems.
  • Demons of Los Alamos, The

    Marchando, Sydney
    The story of Louis Slotin and the Demon Core, for example, is one narrative from the Manhattan Project that has only just reemerged. Recently, enough information from a variety of sources has allowed a more detailed picture of Louis Slotin to develop, highlighting not only his contributions to the Manhattan Project but also his character and the human faults that led to his fatal accident.
  • Laboratory spotlight Carreon lab

    Here at the Carreon lab in Chemical Engineering, our research is focused on the development and application of functional porous materials on the nanoscale.
  • Welcome to the Toberer lab

    If you've ever used computers, instruments, or any electronics, you have probably benefited from the research of Dr. Eric Toberer and his colleagues. Located on the first floor of the General Research Laboratory (GRL), the Toberer Lab has been advancing the frontier of thermoelectrics since 2013.
  • Role of undergraduates in research-an interview with Professor Sullivan, The

    With his optimistic, high-level vision of science and research, Professor Neal Sullivan has successfully led the Colorado Fuel Cell Center (CFCC) for over a decade. From high-profile publications in Science on the characterization of SOFC efficiency to the development groundbreaking electricity storage technologies, the CFCC prevails as one of the premiere research laboratories on campus and in the nation. And, even with all of that success, Sullivan still spends much of his time considering how best to get undergraduates involved with scientific research.
  • Welcome to the MIRRORLab

    Each day, as robotics, AI, and augmented reality become more and more advanced, ever greater challenges arise regarding the interaction between human beings and the technology they create. With this in mind, the purpose of the MIRRORLab is to help make these interactions as natural and productive as possible.
  • A game of telephone: voice multicast in low-power, low-bandwidth mobile wireless networks

    Perry, Ethan
    We don't always realize it, but the devices in our pockets carry much more significance than we often give them credit. Yes, I am talking about cell phones and their flashy graphics, impressive processing power, and stunning cameras. But these features are not the only thing that make cell phones special. Have you ever wondered where all of the information you surf, stream, and download actually comes from? Much of this data is stationed thousands of miles away and makes its way to your phone by means of copper wire, fiber optic cable, and microwaves emitted by cell towers.
  • Research opportunities at Mines

    Harford, Keegan
    For the prospective student researcher, it can be intimidating to find a project to work on. Students, regardless of where they are in their education, are likely to have worries about if they are qualified to work directly with faculty. When first reading about a project that looks interesting, you will inevitably come across words you don't understand. While you may feel underqualified and want to postpone applying for the position, you really shouldn't. In doing so, you would be overlooking your most important qualification: passion. Passion is the quality that makes faculty want to work with you. Even if you don't get a position the first time you apply, you will have demonstrated your desire and commitment, which will make it easier for you to get a position later. Ultimately, I believe that finding the project you are passionate about is the most important step to becoming a researcher. To help with this, I have outlined some of the ways undergraduate students can discover research projects at Mines.
  • Machine learning to investigate the relationship between nutrition and gut biome

    Baker, Lauren
    Machine learning uses automated statistical models and algorithms to investigate patterns and form inferences from data. As a part of the Machine Learning, Informatics, and Data Science team at Mines (MInDS@Mines), one of our core focuses is the development and application of machine learning algorithms to human health conditions whose mechanisms are not well understood. Thus, our interest in the human microbiome is centrally motivated by the microbiome's connection to health conditions.
  • Crowdsourcing as a tool for research

    Kleeman, Hanzelle
    Crowdsourcing platforms are becoming a common tool for researchers around the world. Advocates of these platforms boast that the virtual data collection has many strengths when compared to old-school methods of surveying. Such proponents focus on aspects of convenience and diversity. Unfortunately, serious concerns identified by critical computing scholars remain unaddressed. To better understand these concerns, the research team has completed a comprehensive literature review on the ethics of crowdsourcing, an analysis of published research papers that utilized crowdsourced data, and interviews with crowd workers.
  • Overcoming challenges as an undergraduate researcher

    Monaghan, Austin
    The Tuesday/Thursday slots on my schedule are reserved for something special, and it's not skiing. No, those days are blocked out for research at the High Altitude Observatory (HAO) in Boulder. Although research is technically work, my enthusiasm for it makes it feel like recreation. I almost felt guilty collecting a check this past summer because I knew that, if it really came down to it, I would work for free. That being said, I must confess that many aspects of undergraduate research, from getting a position to managing goals, can prove to be a nuisance for the prospective undergraduate researcher. While I am no expert, I've been lucky enough to spend about three of my undergraduate years conducting research, and I've stepped in enough puddles to give the reader some measure of advice. These "tips and tricks" are based not only on my experiences, but those of my peers. With any luck, the collective knowledge of many undergraduate researchers, socks soaked through with puddle water, can help you avoid some of the common pitfalls of research.
  • Reuleaux undergraduate research magazine: third edition backmatter

    The backmatter includes a request for future authors, a meet the editors section, and a dedication.
  • What secrets do biological vesicles hold? Separation and size characterization of outer membrane vesicles with asymmetrical flow field-flow fractionation and light scattering

    Betz, Elizabeth; Plavchak, Christine; Hansen, Riley; Williams, Kim R.
    Extracellular vesicles (EVs) are nano-vesicles (50-500 nm) that are released by cells and play an important role in cell-to-cell communication. EVs have applications ranging from disease treatment and detection to developing more efficient biofuels. Outer membrane vesicles (OMVs) are a specific type of EV released by gram-negative bacteria. Specifically, OMVs from the soil bacteria Pseudomonas putida, contain enzymes with the ability to break down lignin, a complex plant polymer that is a plentiful resource for biofuels. Studying the relationship of size and content of OMVs within a cultivation of vesicles aids in the understanding of how these OMVs efficiently break down lignin. To investigate P. putida OMVs, we hypothesized that asymmetrical flow field-flow fractionation (AF4), dynamic light scattering (DLS), and multi-angle light scattering (MALS) could be used to efficiently separate and determine the size distributions of OMVs. Liposome standards were utilized in initial experiments to analyze retention times according to size due to their similar structure to OMVs. AF4-DLS-MALS fractionations of P. putida OMVs showed two different sized populations when grown on lignin. Separating these OMV populations will help correlate differences in protein and lipid content between small (50-150 nm) and large (200-500 nm) vesicles.

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