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dc.contributor.advisorPetrella, Anthony J.
dc.contributor.authorHonegger, Jasmin D.
dc.date.accessioned2017-09-11T15:34:17Z
dc.date.accessioned2022-02-03T13:01:10Z
dc.date.available2018-09-08T15:34:17Z
dc.date.available2022-02-03T13:01:10Z
dc.date.issued2017
dc.identifierHonegger_mines_0052N_11340.pdf
dc.identifierT 8348
dc.identifier.urihttps://hdl.handle.net/11124/171598
dc.descriptionIncludes bibliographical references.
dc.description2017 Summer.
dc.description.abstractLow back pain (LBP) is a large problem in the general population and especially among people with a lower-limb amputation (LLA). The primary causes of LBP for people with LLA are whole-body kinematic and muscle asymmetries. However, the sources of LBP are known to exist at the tissue-level such as within the intervertebral discs or facet joint capsules. No previous study has identified the connection between determining the source of pain at the tissue-level and the cause of pain at the whole-body level. Identification of this interconnectivity is required for better understanding of LBP and therapeutic intervention for people with LLA. The purpose of this research was to create a multiscale model of the human lumbar spine in order to help identify and characterize the interconnectivity between whole-body biomechanics and tissue-level metrics leading to LBP for LLA. The results revealed that people with LLA have greater tissue-level loads than able-bodied individuals and suggest that people with LLA may perform certain motions with a more consistent strategy as compared to people without an amputation. These findings help to improve the current understanding of multiscale lumbar spine biomechanics, elucidate the greater risk for LBP in people with LLA, and can help to inform future treatment for biomechanical LBP.
dc.format.mediumborn digital
dc.format.mediummasters theses
dc.languageEnglish
dc.language.isoeng
dc.publisherColorado School of Mines. Arthur Lakes Library
dc.relation.ispartof2010-2019 - Mines Theses & Dissertations
dc.rightsCopyright of the original work is retained by the author.
dc.subjectlow back pain
dc.subjectmultiscale modeling
dc.subjecttranstibial amputation
dc.subjectlumbar spine
dc.subjectfinite element modeling
dc.subjectmusculoskeletal modeling
dc.titleDevelopment of a multiscale model of the lumbar spine: application for persons with a lower-limb amputation
dc.typeText
dc.contributor.committeememberSilverman, Anne K.
dc.contributor.committeememberBerger, John R.
dcterms.embargo.terms2018-09-08
dcterms.embargo.expires2018-09-08
thesis.degree.nameMaster of Science (M.S.)
thesis.degree.levelMasters
thesis.degree.disciplineMechanical Engineering
thesis.degree.grantorColorado School of Mines
dc.rights.accessEmbargo Expires: 09/08/2018


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